The latest from CNN:
Raymond Clark was apprehended about 8:10 a.m. ET at a Super 8 motel in Cromwell, Connecticut, where he had spent the night after being released Wednesday following his submission to DNA testing.
Bond for Clark has been set at $3 million, New Haven Police Chief James Lewis said.
Lewis described the killing as an instance of "workplace violence" but did not elaborate.
Annie Le's body was found in the basement wall of an off-campus medical research building Sunday. She had been strangled.
Le, 24, a pharmacology student, was last seen alive September 8, the day she appeared in a surveillance video entering a four-story lab at 10 Amistad St., about 10 blocks from the main campus.
Her body was found on what was to have been her wedding day.
Lewis said the arrest "went smoothly."